Table 2.
Lipid profile in celiac patients before and after GFD.
| Study (Year) | Study Design | Follow-up | Triglycerides mg/dl | Total Cholesterol mg/dl | LDL mg/dl | HDL mg/dl | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| Before GFD | After GFD | Before GFD | After GFD | Before GFD | After GFD | Before GFD | After GFD | |||
| Tortora (2015) * [32] | Prospective cohort | 1 year | 89.2(±40) (n = 98) p: 0.6 |
92.8(±50) (n = 98) |
- | - | - | - | 51.8(±14) (n = 98) p: 0.1 |
53.8(±14) (n = 98) |
| Tortora (2018) * [33] | Case-control | 4.7(SD ± 1.2) Years | 90.1(±37.8) (n = 370) | 121(±50.3) (n = 370) |
163.7(±35.2) (n = 370) | 179.4(±29.3) (n = 370) | 117.2(±39.1) (n = 370) | 119.8(±38.1) (n = 370) |
54.4(±13) (n = 370) |
54.2(±12.8) (n = 370) |
| Ciccone (2019) ** [35] | Retrospective cohort | 7 years (Range 1–36) | 127.0(60-321) (n = 26) p: 0.0006 | 163.0(151-332) (n = 26) | 191(90.0-322) (n = 88) p:0.0001 | 228(201-33) (n = 88) | - | - | F = 48(27.0—70.0) (n = 70) p:0.0001 M = 52(34.0-67.0) (n = 16) p:0.0001 |
F = 35(19—49) (n =7 0) M = 33(26—59) (n = 16) |
Note: CD, Celiac Disease; GFD: Gluten-free diet; SD, Standard Deviation * Mean (±SD); ** Median (Range).