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. 2020 Apr 22;12(4):1166. doi: 10.3390/nu12041166

Figure 8.

Figure 8

Effects of LBE and RA on the expression of oxidative stress-regulating genes in MCD diet-fed db/db mice. (A) Hepatic protein, (B) the densitometric analysis of WB, and (C) mRNA expression of NRF2 and SOD1. (D) Hepatic mRNA expression of macrophage inflammatory protein-1 alpha (MIP-1ɑ) and intercellular adhesion molecule 1 (ICAM-1). (E) Phosphorylation of AMPK and (F) the densitometric analysis of WB in MCD diet-fed mice treated with LBE or RA. GAPDH was as an internal control for WB analysis and β-Actin was used for mRNA expression. Results are expressed as the mean ± SD (% control). * p < 0.05 compared with the control group; # p < 0.05, ## p < 0.01, and ### p < 0.001 compared with the control group; * p < 0.05 compared with the MCD diet-fed group (n = 5–6 per group).