Figure 1.

Effect of chondroitin sulfate (SCS) on cell proliferation in colon cancer HCT-116 cells. Colon cancer HCT-116 cells were treated with different concentration (100, 200, 400, 800, and 1000 μg/mL) of SCS and 5-fluorouracil (5-FU; 100 μg/mL) for 24 h. Cell viability was measured by CCK8 cell counting assay and the results were expressed as inhibition rate (%) compared to untreated cells. (A) SCS extracted from sturgeon skull, (B) SCS extracted from sturgeon spine. All results are expressed as mean ± SEM (n = 3). Different superscript letters for each column indicate significant differences (p < 0.05) as compared to every other group.