Table 2.

Details of the patients.

Patient Number	1	2	3	4	5	6	7	8	9
Sex	female	male	female	female	female	female	female	female	male
Age at diagnosis (years)	23	55	16	13	20	31	33	18	29
Family number	1	2	2	3	3	4	5	6	7
Gene mutation (mutation sequence)	not screened	RYR2 (D2216G)	RYR2 (D2216G)	RYR2 (L2432F)	RYR2 (L2432F)	RYR2 (M4002V)	0	0	0
Initial medical treatment	Metoprolol 50 mg/day	no medical treatment	Bisoprolol 2.5 mg/day	Bisoprolol 2.5 mg/day	no medical treatment	Metoprolol 200 mg/day	Propafenone 450 mg/day	Metoprolol 150 mg/day	Propanolol (dosage not available)
Changed medical treatment	refused	no medical treatment	Metoprolol 25 mg/day	Bisoprolol 5 mg/day	no medical treatment	Metoprolol 200 mg/day + Flecainide 200 mg/day	Metoprolol 100 mg/day	Metoprolol 150 mg/day	refused
Current medical treatment	refused	no medical treatment	Metoprolol 100 mg/day	Bisoprolol 5 mg/day + Flecainide 200 mg/day	no medical treatment	Metoprolol 200 mg/day + Flecainide 200 mg/day	Metoprolol 100 mg/day + Flecainide 100 mg/day	refused	refused