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Change in the ratio of carboxylated osteocalcin (cOC) to undercarboxylated osteocalcin (ucOC) from baseline. Subjects were administered 72 µg vitamin K/day (around adequate intake of vitamin K) for four weeks. Data are expressed as mean ± standard deviation of 14–15 subjects. * Significantly different from baseline, p < 0.001. Adapted from [35].
