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. 2020 Apr 24;9(4):537. doi: 10.3390/foods9040537

Table 3.

Antimicrobial activity of Satureja montana ethanolic extract and essential oil, and of the six pure compounds against the Campylobacter jejuni 11,168 efflux pump mutants, in terms of their minimal inhibitory concentrations (MICs). ΔcmeB, lacking functional efflux pump CmeABC; ΔcmeR, lacking repressor of efflux pump CmeABC; ΔcmeF, lacking functional efflux pump CmeDEF; and ΔcmeG, lacking functional efflux pump CmeGH.

Treatment ΔcmeB ΔcmeR ΔcmeF ΔcmeG
MIC (mg/L) FCa MIC (mg/L) FCa MIC (mg/L) FCa MIC (mg/L) FCa
Ethanolic extract 31.25 4 125 1 62.5 2 31.25 4
Essential oil 1000 1 1000 1 1000 1 500 2
Carvacrol 15.25 2 7.81 4 15.62 2 0.97 32
Thymol 7.81 4 7.81 4 31.25 1 1.95 16
Thymoquinone 15.25 2 7.81 4 15.62 2 0.97 32
p-cymene 1000 1 500 2 500 2 500 2
γ-terpinene 500 2 250 4 250 4 500 2
Rosmarinic acid 62.5 4 125 4 125 2 125 2

aFC, Fold change increase in antimicrobial activity of the tested compound in the mutant strain, compared to wild type.