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Effects of FXOH on fatty acid ethanolamide levels in LPS-activated macrophage. (A) LC–MS/MS chromatogram (B–F) palmitoylethanolamide (PEA), oleoylethanolamide (OEA), stearoylethanolamide (SEA), anandamide (AEA), and 2-AG levels were measured by LC–MS/MS assay. RAW264.7 cells were pre-treated with FXOH and then stimulated with lipopolysaccharide (LPS) for 24 h. Data represent the mean ± SEM. ** P < 0.01 compared with the control group, # P < 0.05 compared with the LPS + vehicle group.
