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. 2020 Apr 6;9(4):1033. doi: 10.3390/jcm9041033

Table 2.

Unadjusted and adjusted models for outcomes according to residual inflammatory risk.

Unadjusted Model Adjusted Model
Model 1 Model 2 Model 3
Event Inflammatory Status HR (95% CI) p HR (95% CI) p HR (95% CI) p HR (95% CI) p
All-cause death Persistent high 2.34 (1.64–3.39) <0.001 2.18 (1.53–3.16) <0.001 2.03 (1.39–3.00) <0.001 2.08 (1.41–3.11) <0.001
Increased 2.97 (1.21–3.42) 0.009 2.07 (1.21–3.42) 0.009 1.97 (1.09–3.40) 0.026 2.05 (1.13–3.11) 0.019
Attenuated 1.22 (0.76–1.91) 0.40 1.22 (0.77–1.92) 0.40 1.30 (0.80–2.07) 0.28 1.37 (0.84–2.18) 0.20
MACE Persistent high 2.30 (1.49–3.63) <0.001 2.17 (1.40–3.44) <0.001 2.33 (1.45–3.82) <0.001 2.38 (1.46–3.96) <0.001
Increased 2.13 (1.10–3.92) 0.026 1.96 (0.99–3.66) 0.054 2.24 (1.09–4.34) 0.029 2.35 (1.14–4.58) 0.022
Attenuated 1.82 (1.11–3.01) 0.019 1.76 (1.06–2.92) 0.028 1.94 (1.14–3.30) 0.015 2.00 (1.17–3.43) 0.012

Patients with persistent low residual inflammatory risk (RIR) were used as references. Covariates of the fully adjusted model are as below. Model 1: age, sex, RIR. Model 2: age, sex, RIR, hypertension (HT), chronic kidney disease (CKD), diabetes mellitus (DM), dyslipidemia (DL), body mass index (BMI), smoking status, multivessel disease (MVD), left ventricular ejection fraction (LVEF). Model 3: age, sex, RIR, HT, CKD, DM, DL, BMI, smoking status, MVD, LVEF, low-density lipoprotein-cholesterol, high-density lipoprotein–cholesterol, triglycerides, use of statins. HR, hazard ratio; 95%CI, 95% confidence interval.