Table 2.
Unadjusted and adjusted models for outcomes according to residual inflammatory risk.
Unadjusted Model | Adjusted Model | ||||||||
---|---|---|---|---|---|---|---|---|---|
Model 1 | Model 2 | Model 3 | |||||||
Event | Inflammatory Status | HR (95% CI) | p | HR (95% CI) | p | HR (95% CI) | p | HR (95% CI) | p |
All-cause death | Persistent high | 2.34 (1.64–3.39) | <0.001 | 2.18 (1.53–3.16) | <0.001 | 2.03 (1.39–3.00) | <0.001 | 2.08 (1.41–3.11) | <0.001 |
Increased | 2.97 (1.21–3.42) | 0.009 | 2.07 (1.21–3.42) | 0.009 | 1.97 (1.09–3.40) | 0.026 | 2.05 (1.13–3.11) | 0.019 | |
Attenuated | 1.22 (0.76–1.91) | 0.40 | 1.22 (0.77–1.92) | 0.40 | 1.30 (0.80–2.07) | 0.28 | 1.37 (0.84–2.18) | 0.20 | |
MACE | Persistent high | 2.30 (1.49–3.63) | <0.001 | 2.17 (1.40–3.44) | <0.001 | 2.33 (1.45–3.82) | <0.001 | 2.38 (1.46–3.96) | <0.001 |
Increased | 2.13 (1.10–3.92) | 0.026 | 1.96 (0.99–3.66) | 0.054 | 2.24 (1.09–4.34) | 0.029 | 2.35 (1.14–4.58) | 0.022 | |
Attenuated | 1.82 (1.11–3.01) | 0.019 | 1.76 (1.06–2.92) | 0.028 | 1.94 (1.14–3.30) | 0.015 | 2.00 (1.17–3.43) | 0.012 |
Patients with persistent low residual inflammatory risk (RIR) were used as references. Covariates of the fully adjusted model are as below. Model 1: age, sex, RIR. Model 2: age, sex, RIR, hypertension (HT), chronic kidney disease (CKD), diabetes mellitus (DM), dyslipidemia (DL), body mass index (BMI), smoking status, multivessel disease (MVD), left ventricular ejection fraction (LVEF). Model 3: age, sex, RIR, HT, CKD, DM, DL, BMI, smoking status, MVD, LVEF, low-density lipoprotein-cholesterol, high-density lipoprotein–cholesterol, triglycerides, use of statins. HR, hazard ratio; 95%CI, 95% confidence interval.