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. 2020 Apr 10;12(4):1042. doi: 10.3390/nu12041042

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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EGCG reduces cell viability and increases the apoptosis rate of MDSCs in vitro. (A) Representative plots showing the MDSCs from the spleen of 4T1 tumor-bearing mice before and after sorting. (B) The cell viability of MDSCs was significantly reduced by the indicated concentrations of EGCG for 6 h compared to control group. The effects of EGCG on the cell viability of MDSCs were assessed by CCK8 assay. (C) Apoptosis rate of MDSCs significantly increased after 6 h-EGCG treatment. Representative plots (C) and statistical charts (D) are shown. (E) Cell-cycle analysis of MDSCs after 6 h-EGCG treatment is shown. Data are presented as mean ± SEM. *, p < 0.05; **, p < 0.01; ***, p < 0.001.