Figure 2.

SCE-AA mixture enhances learning and memory. (A), Experimental time-line for the fear-memory test. (B), Fear-conditioning test in mice treated three times at 24-h intervals with SCE, AA, or an SCE and AA mixture (10 mg/kg). Mice injected with a mixture of SCE and AA showed greater freezing behavior than other groups in trial 3. Freezing time, presented as a percentage of total test time, increased linearly with trial number. (C,D), Contextual fear memory (C) and cued fear memory (D) test results, presented as means ± SD (n = 5/group; * p < 0.05, *** p < 0.001 vs. corresponding controls).