Figure 3.

Stromal cells from Wharton’s jelly have a broad differentiation capacity and are able to transform into cells of all three primary germ layers: endoderm, ectoderm, and mesoderm. The endodermal lineages obtained from WJ-MSCs include hepatocytes or pancreatic islet-like cells. Differentiation of WJ-MSCs towards mesodermal lineages resulted in obtaining cells such as osteoblasts, chondroblasts, adipocytes, cardiomyocytes, skeletal muscle cells, or endothelial cells. Transformation of WJ-MSCs into neurons, which are of ectodermal origin, has also been achieved.