Table 2.
Particle size, percentage yield, percent drug content, and entrapment efficiency of uncoated and Eudragit coated chitosan microspheres. The results were subjected to one-way ANOVA (Tukeys Test. Data are presented as mean ± SD (standard deviation); n = 3.
| Formulation code | Dmean (µm) | YP% (%) | LC (%) | EE (%) |
|---|---|---|---|---|
| Ch-PP602:1 | 5.57 | 69.73 ± 0.27 | 18.36 ± 0.71 | 75.26 ± 0.27 |
| Ch-PP604:1 | 6.23 | 78.64 ± 0.76 | 13.91 ± 0.22 | 76.81 ± 0.55 |
| Ch-PP608:1 | 7.16 | 86.15 ± 0.88 | 7.72 ± 0.11 | 87.21 ± 0.33 |
| Ch-PP6010:1 | 7.83 | 89.99 ± 0.70 | 6.99 ± 0.53 | 85.61 ± 0.14 |
| Speed 10 | 9.22 | 89.27 ± 0.45 | 12.91 ± 0.27 | 77.82 ± 0.91 |
| Speed 15 | 7.68 | 91.25 ± 0.34 | 13.84 ± 0.61 | 79.33 ± 0.17 |
| Speed 20 | 6.97 | 90.11 ± 0.56 | 13.25 ± 0.12 | 76.16 ± 0.73 |
| S800.5 | 11.82 | 88.37± 0.66 | 9.36 ± 0.11 | 81.11 ± 0.49 |
| S801.0 | 6.45 | 92.27 ±0.55 | 11.32 ± 0.41 | 83.55 ± 0.81 |
| S801.5 | 6.11 | 90.28± 0.47 | 10.51 ± 0.27 | 82.24 ± 0.77 |