Table 3.
Changes in inflammatory parameters throughout the study. The data are given as medians and ranges, n = 6.
| Parameter | After |
p-Value Flaxseed vs. Placebo |
|||
|---|---|---|---|---|---|
| Run-in | Flaxseed | Wash-out | Placebo | ||
| IL 6 (pg/mL) | 11.0 (7.7–37.0) | 12.7 (8.3–19.3) | 11.4 (7.5–35.7) | 10.2 (7.7–55.0) | p = 0.371 |
| sIL-6R (pg/mL) | 53.1 (45.0–75.1) | 51.3 (41.3–80.3) | 51.9 (38.7–93.0) | 65.9 (42.7–81.0) | p = 0.057 |
| CRP (µg/mL) | 0.46 (0.30–2.93) | 0.41 (0.28–0.88) | 0.54 (0.34–1.50) | 0.53 (0.32–1.10) | p = 0.179 |
| TNFα (pg/mL) | 0.56 (0.39–0.73) | 0.57 (0.31–1.00) | 0.40 (0.35–1.05) | 0.54 (0.28–1.04) | p = 0.654 |
| sgp130 (ng/mL) | 490.0(326.8–1287.0) | 563.0 (304.0–1920.0) | 509.2 (434.5–1067.0) | 507.9 (445.9–579.7) | p = 0.179 |
Abbreviations: IL-6, interleukin 6; sIL-6R, soluble interleukin 6 receptor; CRP, C reactive protein; TNF alpha, tumor necrosis factor-alpha; sgp130, soluble gp130.