Table 2.
Abnormalities during the convalescent and late phase of KD and other clinical findings.
| Abnormalities | Group 1 (n = 23) |
Group 2 (n = 177) |
Group 3 (n = 101) |
Total (n = 301) |
p ** |
|---|---|---|---|---|---|
| Behavioral abnormalities | 2 (8.7%) | 89 (50.3%) | 73 (72.3%) | 164 (54.5%) | 0.000 |
| Sensorineural hearing loss | 0 (%) | 29 (16.3%) | 11 (10.8%) | 41 (13.6%) | 0.060 |
| Beau’s lines | 2 (8.7%) | 57 (32.2%) | 43 (42.6%) | 102 (33.9%) | 0.007 |
| Nervous system abnormalities * | 1 (4.3%) | 3 (1.7%) | 5 (5.0%) | 9 (3.0%) | 0.286 |
| Disease recurrences | 0 (0%) | 21 (11.9%) | 4 (4.0%) | 25 (8.3%) | 0.024 |
| Coronary artery abnormalities | 12 (52.2%) | 38 (21.5%) | 34 (33.7%) | 84 (27.9%) | 0.002 |
| Abnormalities noncoronary arteries | 2 (8.7%) | 3 (8.7%) | 3 (3.0%) | 8 (2.7%) | 0.157 |
| Unresponsiveness to IVIG | 6 (26.1%) | 23 (13.0%) | 14 (13.9%) | 43 (14.3%) | 0.240 |
| Aseptic meningitis | 2 (8.7%) | 1 (0.6%) | 0 (0%) | 3 (1.0%) | 0.019 |
| Perianal desquamation | 10 (43.5%) | 102 (57.6%) | 35 (34.7%) | 147 (48.8%) | 0.001 |
| Pneumonitis | 3 (13.0%) | 54 (30.5%) | 13 (12.9%) | 70 (23.3%) | 0.002 |
| Gallbladder hydrops | 0 (0%) | 6 (3.4%) | 0 (0%) | 6 (2.0%) | 0.156 |
| Extreme Irritability | 14 (60.9%) | 129 (72.9%) | 90 (89.1%) | 233 (77.4%) | 0.001 |
| Diarrhea | 5 (21.7%) | 65 (36.7%) | 26 (25.7%) | 96 (31.9%) | 0.093 |
| Vomiting | 6 (26.1%) | 54 (30.5%) | 27 (26.7%) | 87 (28.9%) | 0.763 |
| Arthralgia, arthritis | 0 (0%) | 15 (8.5%) | 15 (14.9%) | 30 (10.0%) | 0.062 |
| Orchitis | 0 (0%) | 5 (2.8%) | 5 (5.0%) | 10 (3.3%) | 0.467 |
| Jaundice | 0 (0%) | 5 (2.8%) | 3 (3.0%) | 8 (2.7%) | 0.804 |
| Peripheral gangrene | 1 (4.3%) | 0 (0%) | 1 (1.0%) | 2 (0.7%) | 0.066 |
| Erythema and induration at BCG inoculation site | 8 (34.8%) | 5 (2.8%) | 0 (0%) | 13 (4.3%) | 0.000 |
Group 1: ≤1 year, Group 2: >1 to ≤4 years, and Group 3: >4 years. * Seizures, chorea, facial paralysis, and learning deficit. ** Pearson chi-square test with Monte Carlo approximation. *** Red: the age groups did not differ statistically (p > 0.005). Blue: abnormalities or clinical findings with higher frequency in older age groups. Green: abnormalities or clinical findings with higher frequency in younger age groups. Black: the highest frequency appeared in the intermediate age group.