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. 2020 Apr 7;9(4):1046. doi: 10.3390/jcm9041046
°C Degrees Celsius
% Percent
3R Reduction, Refinement and Replacement
ARLD Alcohol-related liver disease
ATP Adenosine triphosphate
BMI Body mass index
BQ-123 D-tryptamine-D-aspartic acid-L-proline-D-valine-L-leucine
cAMP Cyclic adenosine monophosphate
CD4 Cluster of differentiation 4
CD25 Cluster of differentiation 25
CD127 Cluster of differentiation 127
CIT Cold ischaemia time
CO2 Carbon dioxide
COPE Consortium for Organ Preservation in Europe
Cy3 Cyanine Cy3
DAA Direct-acting antivirals
DCD Donors after circulatory death
DNA Deoxyribonucleic acid
EAD Early allograft dysfunction
ECD Extended criteria donor
FOXP3 Forkhead box P3
GMP Good manufacturing practice
GW7647 2-(4-(2-(1-Cyclohexanebutyl)-3-cyclohexylureido)ethyl)-phenyl-thio)-2-methyl-propionic acid
GW501516 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]-acetic acid
h Hour/hours
HBD Heart-beating donor
HCV Hepatitis C virus
HLSC Human liver stem-like cells
HMP Hypothermic machine perfusion
IFN-γ Interferon gamma
IL-1 Interleukin 1
IL-6 Interleukin 6
IL-17 Interleukin 17
IRAK-4 Interleukin-1 receptor-associated kinase 4
IRI Ischaemia reperfusion injury
kg/m2 Kilogram per square meter
LD Lipid droplet
LDLT Living donor liver transplant
MaS Macrovesicular steatosis
mRNA Messenger RNA
miRNA MicroRNA
MSC Mesenchymal stem cells
MSC-EV Extracellular vesicles of mesenchymal stem cells
NAFLD Non-alcoholic fatty liver disease
NMP Normothermic machine perfusion
O2 Oxygen
PGE1 Prostaglandin E1
PNF Primary non-function
PPARα Peroxisome proliferator-activated receptor alpha
PPARδ Peroxisome proliferator-activated receptor delta
PRS Post reperfusion syndrome
RNA Ribonucleic acid
RNAi RNA interference
ROS Reactive oxygen species
SCS Static cold storage
SEC Sinusoidal endothelial cell
shRNA Short hairpin RNA
siRNA Small interfering RNA
SNMP Sub-normothermic machine perfusion
TG Triacylglycerol
TNF-α Tumour necrosis factor alpha
Treg Regulatory T cell
UNHBD Uncontrolled non-heart-beating donor