°C |
Degrees Celsius |
% |
Percent |
3R |
Reduction, Refinement and Replacement |
ARLD |
Alcohol-related liver disease |
ATP |
Adenosine triphosphate |
BMI |
Body mass index |
BQ-123 |
D-tryptamine-D-aspartic acid-L-proline-D-valine-L-leucine |
cAMP |
Cyclic adenosine monophosphate |
CD4 |
Cluster of differentiation 4 |
CD25 |
Cluster of differentiation 25 |
CD127 |
Cluster of differentiation 127 |
CIT |
Cold ischaemia time |
CO2
|
Carbon dioxide |
COPE |
Consortium for Organ Preservation in Europe |
Cy3 |
Cyanine Cy3 |
DAA |
Direct-acting antivirals |
DCD |
Donors after circulatory death |
DNA |
Deoxyribonucleic acid |
EAD |
Early allograft dysfunction |
ECD |
Extended criteria donor |
FOXP3 |
Forkhead box P3 |
GMP |
Good manufacturing practice |
GW7647 |
2-(4-(2-(1-Cyclohexanebutyl)-3-cyclohexylureido)ethyl)-phenyl-thio)-2-methyl-propionic acid |
GW501516 |
2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]-acetic acid |
h |
Hour/hours |
HBD |
Heart-beating donor |
HCV |
Hepatitis C virus |
HLSC |
Human liver stem-like cells |
HMP |
Hypothermic machine perfusion |
IFN-γ |
Interferon gamma |
IL-1 |
Interleukin 1 |
IL-6 |
Interleukin 6 |
IL-17 |
Interleukin 17 |
IRAK-4 |
Interleukin-1 receptor-associated kinase 4 |
IRI |
Ischaemia reperfusion injury |
kg/m2
|
Kilogram per square meter |
LD |
Lipid droplet |
LDLT |
Living donor liver transplant |
MaS |
Macrovesicular steatosis |
mRNA |
Messenger RNA |
miRNA |
MicroRNA |
MSC |
Mesenchymal stem cells |
MSC-EV |
Extracellular vesicles of mesenchymal stem cells |
NAFLD |
Non-alcoholic fatty liver disease |
NMP |
Normothermic machine perfusion |
O2
|
Oxygen |
PGE1 |
Prostaglandin E1 |
PNF |
Primary non-function |
PPARα |
Peroxisome proliferator-activated receptor alpha |
PPARδ |
Peroxisome proliferator-activated receptor delta |
PRS |
Post reperfusion syndrome |
RNA |
Ribonucleic acid |
RNAi |
RNA interference |
ROS |
Reactive oxygen species |
SCS |
Static cold storage |
SEC |
Sinusoidal endothelial cell |
shRNA |
Short hairpin RNA |
siRNA |
Small interfering RNA |
SNMP |
Sub-normothermic machine perfusion |
TG |
Triacylglycerol |
TNF-α |
Tumour necrosis factor alpha |
Treg |
Regulatory T cell |
UNHBD |
Uncontrolled non-heart-beating donor |