Table 1.

Ischaemia Reperfusion Injury.

Study	Model	N	Preservation Details/Groups	Length of NMP	Therapeutic Agent(s)	Outcome
Gillooly et al. 2019 [29]	Rat	N/A	HMP ± siRNA, NMP ± SiRNA,	4 h	Fas-short interfering RNA (siRNA)	Diffuse uptake of siRNA in both NMP and HMP groups, with increased uptake in the latter.
Beal et al. 2019 [30]	Rat	6 per group	NMP, NMP + Enkephalin	4 h	Enkephalin	Reduced hepatocyte oxidative stress and mitochondrial dysfunction via opioid receptor signalling.
Moore et al. 2017 [27]	Rat	N/A	NMP	6 h	p53 siRNA-cy3	Positive fluorescence for cy3 detected in NMP livers.

HMP: Hypothermic Machine Perfusion; siRNA: small interfering ribonucleic acid; Enkephalin: D-Ala2, D-Leu5 (DADLE); cy3-dye.