Table 4.
Target genes, functional pathways and the miRs in nephrotic DN patients.
| PI3K-Akt Signaling Pathway | MAPK Signaling Pathway | Human Papillomavirus Infection | |||
|---|---|---|---|---|---|
| Target Genes | miRs | Target Genes | miRs | Target Genes | miRs |
| EIF4E | miR-548p | MAP3K7 | miR-548p | FZD3 | miR-23c |
| FGFR1 | miR-548p | FGFR1 | miR-548p | ||
| PRLR | miR-548p, miR-23c | MKNK2 | miR-548ah-3p | HDAC2 | miR-548p, miR-548ah-3p |
| CCND1 | miR-548ah-3p | TGFBR1 | miR-548ah-3p | CCND1 | miR-548ah-3p |
| PRKAA2 | miR-548ah-3p | RPS6KA3 | miR-548ah-3p | ATP6V0A2 | miR-548ah-3p |
| PPP2R5E | miR-548ah-3p | NF1 | miR-548ah-3p | PPP2R5E | miR-548ah-3p |
| AKT3 | miR-320e | AKT3 | miR-320e | AKT3 | miR-320e |
| CDK6 | miR-320e | STK4 | miR-320e | CDK6 | miR-320e |
| FGF1 | miR-760 | FGF1 | miR-760 | ||
| PDPK1 | miR-760 | ||||
| Ras Signaling Pathway | Endocytosis Pathway | Signaling Pathways Regulating Pluripotency of Stem Cells | |||
| Target Genes | miRs | Target Genes | miRs | Target Genes | miRs |
| FGFR1 | miR-548p | DNM3 | miR-548p | FGFR1 | miR-548p |
| NF1 | miR-548ah-3p | TGFBR1 | miR-548ah-3p | IL6ST | miR-188-5p, miR-320e |
| AKT3 | miR-320e | CHMP1B | miR-548ah-3p | AKT3 | miR-320e |
| STK4 | miR-320e | NEDD4L | miR-23c | ZFHX3 | miR-548ah-3p |
| KSR2 | miR-320e, miR-760 |
CBL | miR-760 | SKIL | miR-548ah-3p |
| FGF1 | miR-760 | SNX1 | miR-760 | FZD3 | miR-548ah-3p, miR-23c |
| SMAD4 | miR-760 | ||||
Background color is simply for better visualization.