Table 1.
Baseline clinical characteristics in recurrent pregnancy loss (RPL) patients and control subjects.
| Characteristic | Control (n = 272) | RPL (n = 361) | P-Value |
|---|---|---|---|
| Age (years) | 32.5 ± 4.02 | 32.5 ± 3.92 | 0.650 |
| BMI (kg/m2) | 21.6 ± 3.2 | 21.5 ± 3.92 | 0.754 |
| Previous pregnancy losses (n) | N/A | 3 ± 1.53 | |
| Live births (n) | 1.71 ± 0.58 | N/A | |
| Mean gestational age (weeks) | 39.1 ± 1.59 | 7.4 ± 1.94 | |
| PT (sec) | 11.2 ± 2.81 | 11.6 ± 0.87 | <0.0001 |
| aPTT (sec) | 30.7 ± 4.65 | 32.3 ± 4.38 | 0.006 |
| PLT (103/μl) | 238.3 ± 59.66 | 254.8 ± 55.85 | 0.004 |
| Folate (mg/ml) | 14 ± 8.52 | 14.3 ± 12.21 | 0.918 |
| Total cholesterol (mg/dl) | 239.5 ± 88.39 | 187.1 ± 49.34 | 0.006 |
| Uric acid (mg/dl) | 4.1 ± 1.5 | 3.8 ± 0.85 | 0.600 |
| BUN (mg/dl) | 8 ± 2.02 | 9.9 ± 2.69 | 0.0001 |
| Creatinine (mg/dl) | 0.7 ± 0.08 | 0.7 ± 0.12 | 0.076 |
| E2 (Basal) | 26 ± 14.75 | 35.4 ± 29.37 | 0.003 |
| TSH (mU/l) | N/A | 2.2 ± 1.57 | |
| FSH (mU/l) | 8.1 ± 2.85 | 7.4 ± 10.72 | <0.0001 |
| LH (mU/l) | 3.3 ± 1.74 | 6.3 ± 12.38 | <0.0001 |
| Prolactin (ng/ml) | N/A | 16 ± 13.22 | |
| HDL (mg/dl) | N/A | 61.6 ± 18.14 | |
| Hct (%) | 35.5 ± 4.22 | 37.4 ± 3.37 | <0.0001 |
| PAI-1 (ng/ml) | N/A | 10.5 ± 5.74 | |
| Hcy | N/A | 6.9 ± 2.13 | |
| TG (mg/dl) | N/A | 179.1 ± 156.51 | |
| CD56 (NK cells) | N/A | 18.4 ± 8.04 |
Data are presented as the mean ± standard deviation (SD). RPL, recurrent pregnancy loss; BMI, body mass index; PT, prothrombin time; aPTT, activated partial thromboplastin time; PLT, platelets; BUN, blood urea nitrogen; E2, estradiol; TSH, thyroid-stimulating hormone; FSH, follicle-stimulating hormone; LH, luteinizing hormone; HDL, high-density lipoprotein; Hct, hematocrit; PAI-1, plasminogen activator inhibitor-1; Hcy, homocysteine; TG, triglycerides; NK, natural killer. Significant P-values are marked in bold.