Table 1:
Baseline Characteristics
| Linagliptin (n=128) | Basal Bolus (n=122) | p-value | |
|---|---|---|---|
| Age, years | 58 ± 11 | 58 ± 12 | 0.99 |
| Female, n (%) | 66 (52) | 58 (48) | 0.52 |
| BMI, kg/m2 | 35.4 ± 8.5 | 32.6 ± 6.9 | 0.02 |
| Weight, kg | 101.7 ± 24.8 | 94.6 ± 22.3 | 0.04 |
| Race, n (%) | 0.67 | ||
| White | 44 (35) | 46 (38) | |
| Black | 59 (46) | 58 (48) | |
| Other | 25 (19) | 18 (15) | |
| Duration of Diabetes, years | 8 ± 7 | 9 ± 8 | 0.47 |
| Length of stay, days (median, IQR) | 4 (3, 5) | 3 (3, 6) | 0.76 |
| Admission BG, mg/dl | 9.7 ± 4.2 | 9.9 ± 3.8 | 0.39 |
| Admission HbA1c, mmol/mol | 60 ± 20.8 | 64 ± 21.9 | 0.04 |
| Randomization BG, mmol/L | 10.7 ± 2.2 | 11.0 ± 2.3 | 0.26 |
| Admission diabetes therapy, n (%) | 0.41 | ||
| No medications | 15 (12) | 9 (7.4) | |
| OAD only | 89 (70) | 81 (66) | |
| Insulin only | 11 (8.6) | 14 (11) | |
| OAD + Insulin | 13 (10) | 18 (15) | |
| Type of Surgery, n (%) | |||
| Orthopedic | 51 (40) | 50 (41) | 0.85 |
| Abdominal | 14 (11) | 7 (5.7) | 0.17 |
| Urologic | 11 (8.6) | 10 (8.2) | 1.00 |
| Amputation | 6 (4.7) | 12 (9.8) | 0.14 |
| Gynecologic | 10 (7.8) | 9 (7.4) | 1.00 |
| I&D | 9 (7) | 9 (7.4) | 1.00 |
| Head & Neck | 1 (0.8) | 5 (4.1) | 0.11 |
| Other | 26 (20.3) | 20 (16.4) | 0.45 |
All data are expressed as mean ± SD unless otherwise specified. IQR: interquartile range, OAD: oral antidiabetic agent, I&D: Incision and drainage. BG: blood glucose