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. 2020 Apr 18;11(4):444. doi: 10.3390/genes11040444

Table 1.

General Far and Tyr roles in Candida.

Quorum-sensing Molecule Activity Reference(s)
Farnesol Inhibition of hypha formation, filamentation, and biofilm formation/development [6,13,14,27,28]
Regulation of drug efflux and apoptosis [4,5,14,28]
Anti-cancer/anti-tumor, anti-inflammatory, anti-allergic, and anti-obesity [14]
Fungicidal, antimicrobial [14]
Inhibition of the transition from the oval/spherical cell morphotype to hyphal cells [4,20]
Tyrosol Antioxidant [55,56]
Cells’ stimulation of a quicker transition from oval/spherical cell to hyphal form [11,59]
Induction of germ tube formation [11]
Stimulation of firm adherence of the cells to surfaces [59]
Initiation of biofilm formation [60]
Antifungal [60]