Table 1.
Intervention Period (Weeks) | 0 | 2 | 3 | 4 | 5 | 6 | 8 | 12 |
(Weeks since UV Irradiation) | (0) | (1) | (2) | (3) | (4) | (6) | (10) | |
Precheck | ● | |||||||
Visit to facility | ● | ● | ● | ● | ● | ● | ● | ● |
Informed consent | ● | |||||||
MED evaluation | ● | |||||||
Evaluation of pigmentation | ||||||||
UV-irradiation (1.5 MED) | ● | |||||||
Erythema, melanin, L value | ● | ● | ● | ● | ● | ● | ● | |
Evaluation of facial skin condition | ||||||||
Water content, TEWL | ● | ● | ● | ● | ||||
Ingestion of test sample | ||||||||
Recording in diary |
MED: minimal erythema dose; TEWL: trans-epidermal water loss. ●: visits for the measurement.