Figure 1.
Overview of the cell-encapsulation device. (A) A 3D printed capsule with ARPE-19 cells enclosed inside the device. ARPE-19 cells were cultured in polystyrene (PS) sheets. (B) Cross-section of device in A. The 3D printed capsule with semi-porous membrane (PEGDM) allowed selective permeability of brain-derived neurotrophic factor (BDNF; 27 kDa), O2, and nutrients (16–180 Da) while protecting the cells from the immune response of the body (i.e., immunoglobulin (IgG; 150 kDa)).
