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. 2020 Mar 4;91(5):547–559. doi: 10.1136/jnnp-2019-322375

Table 5.

Stimulation of the dorsal fornix or the mammillothalamic tract in rodent models

Outcome Species Stimulation frequency (Hz) Dorsal fornix Mammillothalamic tract
Thalamic theta oscillations Rat 1 Increase of theta power (Tsanov et al 2011c) No increase of theta power (Tsanov et al 2011c)
100 No increase of theta power
(Tsanov et al 2011c)
No increase of theta power (Tsanov et al 2011c)
Thalamic synaptic plasticity Rat 1 LTD of FP slope and amplitude (Tsanov et al 2011d) LTP of FP slope and amplitude (Tsanov et al 2011d)
100 LTP of the FP slope, no effect on FP amplitude (Tsanov et al 2011d) LTP of FP slope and amplitude (Tsanov et al 2011d)
Biochemistry Rat scopolamine IP (0.1 mg/kg) 10 c-Fos increase in infralimbic and prelimbic cortices (Hescham et al 2015b)
100
Memory Rat scopolamine IP (0.1 mg/kg) 10 No effect on object location task (Hescham et al 2015b)
100 No effect on object location task (Hescham et al 2015b)

FP, field potential; IP, intraperitoneal; LTD, long-term depression; LTP, long-term potentiation.