1. Total distance and movement provide information about general activity of tree shrews and mice.

A: Total distance moved by tree shrews and mice in box during 5 min open-field test and every 2.5 min (left). Heatmaps show locomotor activity expressed as distance traveled in successive 1 min bins in open-field test over a 5 min period for each tree shrew and mouse (right). B: Total cumulative duration of movement (moving) of tree shrews and mice in open-field box during a 5 min sample period and every 2.5 min. Values are means±SEM (tree shrew: n=19; mouse: n=23).