Skip to main content
. Author manuscript; available in PMC: 2020 May 17.
Published in final edited form as: Cell Rep. 2019 Apr 30;27(5):1364–1375.e5. doi: 10.1016/j.celrep.2019.04.013

Figure 2. MCU Is Largely Dispensable for Brown Fat Bioenergetics.

Figure 2.

(A) Core body temperature of mice transferred from room temperature to 4°C (n = 5–6 per group). Full body temperature data over time is presented in Figure S3A.

(B) Core body temperature of mice transferred to 4°C following 1 week habituation to 30°C (n = 7 per group). Full body temperature data over time is presented in Figure S3B.

(C and D) Body mass of male (C) and female (D) —Cre and +Cre animals fed high-fat diet. Full body mass data over time is presented in Figures S3C and S3D.

(E) Brown fat pyruvate dehydrogenase (PDH) phosphorylation in —Cre or +Cre mice with or without ad libitum access to food at room temperature for 6 h. Animals were starved for 12 h overnight prior to the experiment.

(F) Brown fat pyruvate dehydrogenase (PDH) phosphorylation in —Cre or +Cre mice fasted at room temperature or 4°C for 6 h.

Results are reported as mean + SEM.