Extended Data Fig. 6. PIF7 and PIF4 are likely to interact.
a Venn diagram showing the overlap between PIF7-MYC and PIF4-HA ChIP-seq peaks. p-value was obtained by Fisher’s exact test for the independence of the two gene sets in comparison with the genomic background (n = 33554).
b IGV browser view of PIF7-MYC and PIF4-HA binding in the ATHB2 promoter.
c Yeast-2-hybrid assay testing interaction of PIF4 and PIF7 proteins expressed as fusions to a GAL4 binding domain (BD) or activation domain (AD). Empty vectors expressing BD and AD served as negative controls. The experiment was repeated once with similar results.