TABLE 4.
Calculation of H-ARs from AIs1
| Nutrient | IOM AI – Children2 | IOM AI – Adults | EFSA AI – Children2 | EFSA AI – Adults | WHO/FAO RNI – Children | WHO/FAO RNI – Adults | H-AR – Children3 decision | H-AR – Adults3 decision |
|---|---|---|---|---|---|---|---|---|
| Pantothenic acid, mg/d | 2–5 | 5 | 4–5 | 5 | 2–5 | 5 | 3.2–4.0 | 4.0 |
| Biotin, μg/d | 8–25 | 30 | 20–35 | 40 | 8–25 | 30 | 16–28 | 32 |
| Choline, mg/d | 200–550 | 425–550 | 140–400 | 400 | — | — | 112–320 | 320 |
| Chromium, μg/d | 11–35 | 25–35 | — | — | — | — | 8.8–28 | 20–28 |
| Fluoride, mg/d | 0.7–3.0 | 3.0–4.0 | 0.6–3.2 | 2.9–3.4 | — | — | 0.48–2.6 | 2.3–2.7 |
| Manganese, mg/d | 1.2–2.2 | 1.8–2.3 | 0.5–3.0 | 3.0 | — | — | 0.4–2.4 | 2.4 |
1
Calculations assumed a CV of 12.5%. The H-AR was calculated as 80% of the AI, so that the AI is 2 × CV (25%) greater than the H-AR. See Table 2 for a summary of the final H-AR values. AI, adequate intake; EFSA, European Food Safety Authority; H-AR, harmonized average requirement; IOM, Institute of Medicine; RNI, recommended nutrient intake.
2
Age ranges for children are 1–17 y for EFSA and 1–18 y for IOM and FAO/WHO.
3
H-ARs use EFSA values except IOM values for chromium.