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. 2020 Apr 22;21(6):746–755. doi: 10.3348/kjr.2020.0215

Table 1. Clinical and Laboratory Characteristics of Included Patients.

Fibrosis Group (n = 14) Non-Fibrosis Group (n = 18) P
Clinical characteristic
 Age (year) 54.0 (49.0–65.3) 37.0 (30.5–52.5) 0.008
 Male: female ratio 12:2 10:8 0.124
Comorbidity
 Diabetes 1 (7.1) 1 (5.6) > 0.050
 Hypertension 4 (28.6) 0 (0) 0.028
 Cardiac disease 1 (7.1) 1 (5.6) > 0.050
 Chronic obstructive pulmonary disease 1 (7.1) 0 (0) 0.437
Signs and symptoms
 Fever 14 (100) 13 (72.2) 0.052
 Dyspnea 6 (42.9) 1 (5.6) 0.027
 Cough 6 (42.9) 9 (50.0) 0.735
 Fatigue 7 (50.0) 7 (38.9) 0.721
 Muscle ache 5 (35.7) 3 (16.7) 0.252
 Diarrhea 0 (0) 2 (11.1) 0.492
 Respiratory rate (breaths per min) 20.0 (18.8–27.8) 18.5 (18.0–20.0) 0.026
Laboratory examinations
 White blood cell count (x109/L) 3.8 (2.8–5.4) 4.0 (2.9–4.4) 0.687
 Lymphocyte count (x109/L) 0.6 (0.4–0.9) 1.1 (0.8–1.3) 0.003
 Lactic dehydrogenase (U/L) 289.0 (179.0–428.5) 180.0 (148.5–191.0) 0.014
 Creatine kinase (U/L) 112.0 (68.0–203.5) 62.0 (51.5–114.5) 0.031
 C-reactive protein (mg/L) 53.4 (29.6–111.2) 10.0 (5.2–23.6) 0.002
 Alanine transaminase (U/L) 52.0 (31.0–142.0) 23.5 (12.0–39.0) 0.021
 Creatinine (μmol/L) 81.2 (73.1–94.8) 69.1 (61.5–80.3) 0.029
 Interleukin-6 (pg/mL) 79.7 (10.5–98.3) 11.2 (4.4–19.2) 0.040
Treatment
 Pulsed steroid therapy 11 (78.6) 10 (55.6) 0.266
 Days of pulsed steroid therapy 11.0 (8.0–13.0) 5.0 (3.0–6.3) < 0.001
 Antiviral therapy 14 (100) 18 (100) -
 Days of antiviral therapy 12.0 (9.5–14.8) 6.5 (5.0–12.0) 0.012
Others
 Length of hospital stay (day) 19.5 (11.5–21.8) 10.0 (6.0–15.3) 0.001
 Intensive care unit admission 5 (35.7) 0 (0) 0.010
 Days from illness onset to initial CT scan 5.5 (3.0–7.3) 2.5 (1.0–5.3) 0.039
 Days from illness onset to worst CT scan 11.0 (7.0–15.0) 9.5 (6.5–11.0) 0.042
 Days after discharge to latest follow-up CT scan 9.0 (7.0–11.0) 9.0 (7.8–11.3) -

Data are median (interquartile range) or n (%).