Table 2. Univariate and Multivariate Survival Analysis.
| Variables | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
| Hazard Ratio (95% CI) | P | Hazard Ratio (95% CI) | P | |
| Age | 1.01 (0.98–1.04) | 0.253 | ||
| Sex | 0.153 | |||
| Male | 1 (reference) | |||
| Female | 0.60 (0.30–1.20) | |||
| Karnofsky performance | 0.426 | |||
| < 70 | 1 (reference) | |||
| ≥ 70 | 0.66 (0.25–1.72) | |||
| Genetic information | ||||
| Methylated MGMT promoter | 0.041 | 1.96 (0.92–4.14) | 0.070 | |
| Negative | 2.07 (1.05–4.10) | |||
| Positive | 1 (reference) | |||
| IDH mutation | 0.448 | |||
| Mutant | 0.64 (0.19–2.13) | |||
| Wild type | 1 (reference) | |||
| Tumor volume | ||||
| CEL | 0.99 (0.99–1.00) | 0.433 | ||
| NE-T2HSIL | 1.00 (0.99–1.01) | 0.177 | ||
| DCE parameters | ||||
| CEL | ||||
| Ktrans_mean | 553.08 (2.26–134799.10) | 0.032 | 553.08 (2.27–134756.74) | 0.024 |
| Ktrans_95th | 4.85 (0.91–25.70) | 0.083 | 1.85 (0.03–111.03) | 0.733 |
| Ve_mean | 1.01 (0.99–1.02) | 0.294 | ||
| Ve_95th | 1.00 (0.99–1.01) | 0.324 | ||
| NE-T2HSIL | ||||
| Ktrans_mean | 4.28 × 10-15 (1.79 × 10-43–102.19 × 1012) | 0.291 | ||
| Ktrans_95th | 0.66 (0.00–1544.07) | 0.935 | ||
| Ve_mean | 0.87 (0.64–1.17) | 0.338 | ||
| Ve_95th | 0.99 (0.95–1.03) | 0.711 | ||
CI = confidence interval, DCE = dynamic contrast-enhanced, Ktrans = volume transfer constant, Ve = volume of extravascular extracellular space