Table 1. Comparison of Myocardial Characterization according to Time Points and Groups.
| Variable | 24 h | 48 h | 72 h | Day 5 | Group | Time | Group x Time | |||
|---|---|---|---|---|---|---|---|---|---|---|
| F | P | F | P | F | P | |||||
| Infarct size (%) | 23.627 | < 0.001 | 143.011 | < 0.001 | 1.017 | 0.361 | ||||
| Control (n = 10) | 26.7 ± 5.7 | 25.7 ± 6.0 | 21.5 ± 6.0 | 16.2 ± 4.0 | ||||||
| APT102 (n = 10) | 18.0 ± 4.8 | 17.1 ± 4.3 | 11.6 ± 2.6 | 5.8 ± 1.5 | ||||||
| Edema size (%) | 19.016 | < 0.001 | 115.878 | < 0.001 | 1.780 | 0.190 | ||||
| Control (n = 10) | 30.2 ± 4.4 | 30.8 ± 3.9 | 26.8 ± 3.5 | 20.0 ± 2.5 | ||||||
| APT102 (n = 10) | 24.0 ± 5.0 | 24.4 ± 6.5 | 18.2 ± 4.8 | 11.2 ± 2.9 | ||||||
| IMH size (%) | 7.646 | 0.013 | 35.742 | < 0.001 | 0.115 | 0.886 | ||||
| Control (n = 10) | 3.9 ± 2.0 | 5.2 ± 2.3 | 3.7 ± 1.5 | 2.7 ± 1.1 | ||||||
| APT102 (n = 10) | 2.3 ± 1.3 | 3.4 ± 1.8 | 2.1 ± 1.1 | 0.9 ± 0.6 | ||||||
| MVO size (%) | 4.444 | 0.049 | 175.394 | < 0.001 | 0.735 | 0.463 | ||||
| Control (n = 10) | 3.8 ± 0.8 | 3.1 ± 0.9 | 2.3 ± 0.6 | 1.0 ± 0.3 | ||||||
| APT102 (n = 10) | 3.3 ± 0.8 | 2.7 ± 0.7 | 1.7 ± 0.5 | 0.6 ± 0.3 | ||||||
| LVMV (mm3) | 0.122 | 0.731 | 22.642 | < 0.001 | 0.695 | 0.487 | ||||
| Control (n = 10) | 8.8 ± 1.0 | 8.8 ± 1.0 | 8.5 ± 1.0 | 8.2 ± 1.0 | ||||||
| APT102 (n = 10) | 8.6 ± 0.8 | 8.6 ± 1.0 | 8.4 ± 0.9 | 8.1 ± 0.8 | ||||||
IMH = intramyocardial hemorrhage, LV = left ventricular, LVMV = left ventricular myocardial volume, MVO = microvascular obstruction