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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Brain Behav Immun. 2019 Nov 18;87:218–228. doi: 10.1016/j.bbi.2019.11.006

Fig. 8.

Fig. 8.

TX spore exposure increased numbers of cells producing the inflammatory cytokine IL-1β in dorsomedial hippocampus. Numbers of IL-1β-ir cells in CA1 were significantly correlated with increased memory of the auditory cue in NTX and TX mice. TX spore exposure significantly increased IL-1β-ir cells in A. dorsomedial CA1 and B. dorsomedial hippocampus. In hippocampus (B), TX mice also had significantly more IL-1β-ir cells than NTX mice. *P < 0.05, **P < 0.01, (Ns). C. Numbers of IL-1β-ir cells in CA1 in spore-treated mice (NTX + TX) correlated strongly with developing greater fear of the auditory cue previously paired with footshock. D. VEH mice did not show this relationship.