Table 2. Comparison between histopathological findings in preoperative liver biopsy in both groups of infants with biliary atresia (n=73).
| Histopathologic findings | Jaundice-free at 6 months (n=27) | Persistent jaundice at 6 months (n=46) | p-value | |
|---|---|---|---|---|
| Distorted lobular architecture | 21 (77.8) | 39 (84.8) | 0.220 | |
| Ductal cholestasis | 8 (29.6) | 13 (28.3) | 0.900 | |
| Bile plugs | 12 (44.4) | 29 (63.0) | 0.013 | |
| Degree of portal fibrosis | 0.790 | |||
| Mild | 5 (18.5) | 7 (15.2) | ||
| Moderate | 14 (51.9) | 27 (58.7) | ||
| Severe | 5 (18.5) | 12 (26.1) | ||
| Fibrous septa | 11 (40.7) | 21 (45.7) | 0.180 | |
| Porto-portal bridging fibrosis | 13 (48.1) | 22 (47.8) | 0.330 | |
| Hepatocellular degeneration | 25 (92.6) | 44 (97.9) | NA | |
| Giant cells | 13 (48.1) | 18 (39.1) | 0.450 | |
| Hyperplastic Von Kupffer cells | 0 (0) | 5 (10.9) | 0.070 | |
Values are presented as number (%).
NA: not applicable.