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. 2020 May 13;23(3):266–275. doi: 10.5223/pghn.2020.23.3.266

Table 2. Comparison between histopathological findings in preoperative liver biopsy in both groups of infants with biliary atresia (n=73).

Histopathologic findings Jaundice-free at 6 months (n=27) Persistent jaundice at 6 months (n=46) p-value
Distorted lobular architecture 21 (77.8) 39 (84.8) 0.220
Ductal cholestasis 8 (29.6) 13 (28.3) 0.900
Bile plugs 12 (44.4) 29 (63.0) 0.013
Degree of portal fibrosis 0.790
Mild 5 (18.5) 7 (15.2)
Moderate 14 (51.9) 27 (58.7)
Severe 5 (18.5) 12 (26.1)
Fibrous septa 11 (40.7) 21 (45.7) 0.180
Porto-portal bridging fibrosis 13 (48.1) 22 (47.8) 0.330
Hepatocellular degeneration 25 (92.6) 44 (97.9) NA
Giant cells 13 (48.1) 18 (39.1) 0.450
Hyperplastic Von Kupffer cells 0 (0) 5 (10.9) 0.070

Values are presented as number (%).

NA: not applicable.