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. 2020 May 12;15:3377–3389. doi: 10.2147/IJN.S233766

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© 2020 Shady et al.

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Analysis of physicochemical properties for the 14 isolated compounds by (A) molecular weight, (B) log P, (C) HBD, (D) HBA, (E) tPSA, and (F) number of rotatable bonds. The green line indicates the maximum desirable value for oral bioavailability defined by Lipinski’s rule of five and Veber’s oral bioavailability rule.