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. 2020 May 13;13:4113–4122. doi: 10.2147/OTT.S245848

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© 2020 Zhu et al.

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Effect of Ibrutinib on viability of PC3 and DU145 cells. Cell viability was assessed using MTT assay method as described in the methods. (A) Concentration-dependent effect Ibrutinib on DU145 viability. Vertical axis: cell viability expressed as percent of control (%); horizontal axis: Ibrutinib concentration (µM). (B) Concentration-dependent effect Ibrutinib on PC3 viability. Vertical axis: cell viability expressed as percent of control (%); horizontal axis: Ibrutinib concentration (µM). (C) Time- and concentration-dependent inhibitory effect of Ibrutinib on DU145 cell proliferation. Vertical axis: Inhibition rate (%); horizontal axis: time (h). (D) Time- and concentration-dependent inhibitory effect of Ibrutinib on PC3 cell proliferation. Vertical axis: Inhibition rate (%); horizontal axis: time (h).