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. 2020 May 11;12:3285–3291. doi: 10.2147/CMAR.S249237

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© 2020 Xue et al.

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Effects of circPRMT5 knockdown on PTC cells. (A) Relative expression of circPRMT5 and PRMT5 after circPRMT5 silencing. (B and C) CCK8 assay and colony formation assay were performed to test cell proliferation. (D and E) Cell migration and invasion were reduced after circPRMT5 silencing by transwell assay. (F) CircPRMT5 knockdown increased the activity of Caspase-3. *p<0.05.