Table 2.

Postoperative opioid (MME) administration.

	All Patients			Opioid Naïve			Opioid Tolerant
	CISB (n = 70)	LBB (n = 34)	P value	CISB (n = 50)	LBB (n = 22)	P value	CISB (n = 20)	LBB (n = 12)	P value
0–4 h	6.0 ± 12.7	2.2 ± 5.1	0.014*	3.3 ± 5.3	1.3 ± 3.8	0.055	12.8 ± 21.0	3.8 ± 6.8	0.60
5–8 h	5.6 ± 8.9	5.3 ± 8.2	0.73	3.5 ± 5.6	3.1 ± 5.5	0.57	10.7 ± 13.0	9.5 ± 10.8	0.94
9–12 h	8.3 ± 8.7	4.9 ± 7.4	0.026*	7.3 ± 7.3	4.1 ± 6.8	0.039*	10.7 ± 11.1	6.4 ± 8.5	0.27
13–16 h	10.4 ± 12.4	7.9 ± 11.6	0.25	7.6 ± 8.7	4.3 ± 5.9	0.12	17.6 ± 17.0	14.6 ± 16.1	0.71
17–20 h	8.5 ± 10.1	7.3 ± 9.4	0.43	6.5 ± 8.0	5.0 ± 6.8	0.41	13.3 ± 12.9	11.6 ± 12.3	0.77
21–24 h	9.1 ± 9.7	6.7 ± 10.1	0.12	6.8 ± 6.2	4.3 ± 9.2	0.03*	14.7 ± 13.9	12.2 ± 10.6	0.78
24–36 h	11.9 ± 17.7	9.5 ± 12.8	0.70	14.4 ± 20.8	8.2 ± 12.3	0.48	6.8 ± 6.6	13.1 ± 15.5	0.55
Total in 24 h	45.7 ± 43.5	32.3 ± 38.2	0.039*	33.2 ± 23.7	21.1 ± 27.3	0.014*	76.8 ± 63.3	52.9 ± 47.4	0.38
Total hospital	54.1 ± 51.0	40.1 ± 50.6	0.028*	42.9 ± 41.3	30.6 ± 46.1	0.016*	82.1 ± 62.4	57.3 ± 55.9	0.25
MME per hour	2.0 ± 2.0	1.5 ± 1.8	0.035*	1.5 ± 1.1	0.9 ± 1.2	0.008*	3.3 ± 3.0	2.5 ± 2.3	0.57

Values are given as the mean plus or minus the standard deviation.

CISB, continuous interscalene nerve block; LBB, liposomal bupivacaine interscalene block; MME, milligram morphine equivalent.

*Indicates statistically significant values (P < 0.05).