Discharge and Refill Opioid Prescription MME within 8 Weeks†
	All Patients			Opioid Naïve			Opioid Tolerant
	CISB (n = 31)	LBB (n = 34)	P value	CISB (n = 25)	LBB (n = 22)	P value	CISB (n = 6)	LBB (n = 12)	P value
Preoperative MME	316 ± 1247	410 ± 711	0.72	–	–	–	1633 ± 2598	1059 ± 793	0.62
Discharge MME	487 ± 379	293 ± 62	0.009*	425 ± 206	293 ± 66	0.005*	745 ± 748	294 ± 56	0.20
Number of refills	0.6 ± 0.8	0.8 ± 1.0	0.22	0.4 ± 0.6	0.5 ± 0.6	0.77	1.2 ± 1.2	1.5 ± 1.2	0.58
Refill MME	270 ± 567	417 ± 680	0.35	157 ± 252	109 ± 164	0.44	738 ± 1141	980 ± 896	0.63
Total postop MME	757 ± 892	710 ± 675	0.81	582 ± 325	402 ± 173	0.021*	1483 ± 1866	1274 ± 878	0.75

Values are given as the mean plus or minus the standard deviation.

CISB, continuous interscalene nerve block; LBB, liposomal bupivacaine interscalene block; MME, milligram morphine equivalents.

*Indicates statistically significant values (P < 0.05).

†Cohort includes patients after July 2017.