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. 2019 Nov 15;22:124–131. doi: 10.1016/j.jot.2019.10.009

Figure 1.

Figure 1

(A) Representative MRI images of ‘normal’ and MCs discs. (B) In human endplate specimens, H&E staining showed homogenous extracellular matrix and small round chondrocytes in the control group versus fibrotic and sclerotic extracellular matrix and fewer chondrocytes in the MCs group. (C) Furthermore, a reduction in the glycosaminoglycan content was observed in the MCs group through Safranin O Fast Green staining, and (D and E) immunohistochemistry demonstrated reduced lubricin expression in the MCs group (Scale bar: 100 ​μm, *p ​< ​0.05, **p ​< ​0.01,***p ​< ​0.005). H&E staining = haematoxylin and eosin staining MRI = magnetic resonance imaging.