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(A–B) The expression of MMP 1(A) and ADAMTS5(B) in endplate chondroctyes stimulated with P. acnes supernatants was increased compared with controls. (C–E) The expression of Sox9(C), collagen type-II(D) and aggrecan(E) in endplate chondroctyes stimulated with P. acnes supernatants significantly decreased compared with controls, and the reduction tended to be greater at the higher concentrations. (*p< 0.05, ** p< 0.01,*** p< 0.005).
