Table 3.
Spearman correlations between CSF biomarkers and total CAPS-IV scores in PTSD.
| Neurobiological Factor Assayed in CSF (Ordered by Strength of Correlation) | Correlation Coefficient (rho) | p-Value |
|---|---|---|
| Allopregnanolone + Pregnanolone (Allo + PA) | −0.69 | 0.01* |
| Interleukin 6 (IL-6) | 0.52 | 0.07 |
| 3α-Androstanediol | −0.39 | 0.24 |
| Neuropeptide Y (NPY) | 0.37 | 0.22 |
| Dehydroepiandrosterone-Sulfate (DHEAS) | 0.32 | 0.31 |
| Dehydroepiandrosterone (DHEA) | 0.26 | 0.34 |
| Testosterone | −0.26 | 0.45 |
| 5α-Dihydroprogesterone (5α-DHP) | −0.25 | 0.43 |
| Gamma-amino-butyric acid (GABA) | 0.20 | 0.52 |
| 5α-Dihydrotestosterone (5α-DHT) | −0.13 | 0.68 |
| 17β-Estradiol | −0.06 | 0.85 |
| Progesterone | 0.06 | 0.85 |
| Norepinephrine (NE) | −0.04 | 0.91 |