Table 1.
Detailed information of the samples.
| OA stage | Amount of tibial plateau | Treatments | Amount of osteochondral plugs | Cartilage thickness (mm) | Modified Mankin gradingb |
Type of diffusion |
||||
|---|---|---|---|---|---|---|---|---|---|---|
| Structure (0–6) | Cellular abnormalities (0–3) | Matrix staining (0–4) | Self-diffusion | Static compression diffusion | Cyclic compression diffusion | |||||
| Early | 4 | TKAa (2), Amputees (2) | n = 8 | 2.53 ± 0.27 | 0.75 ± 0.71 | 0.63 ± 0.51 | 0.75 ± 0.46 | n = 2 | n = 3 | n = 3 |
| Middle | 7 | TKA | n = 12 | 1.87 ± 0.38 | 3.12 ± 0.72 | 1.42 ± 0.90 | 1.92 ± 0.67 | n = 3 | n = 3 | n = 6 |
| Late | 10 | TKA | n = 12 | 1.43 ± 0.54 | 4.92 ± 0.51 | 2.08 ± 0.51 | 3.50 ± 0.67 | n = 3 | n = 4 | n = 5 |
a
TKA: total knee arthroplasty, data are shown as mean ± SD.
b
The modified Mankin score was calculated as a mean of three evaluations independently conducted by three investigators from blind-coded samples.