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. 2019 Jul 30;15(2):67–73. doi: 10.1016/j.joto.2019.07.001

Table 1.

Advantages of intratympanic therapy over systemic steroid treatment.

  • 1

    Targeted drug delivery resulting in higher local concentration of the drug.

  • 2

    No systemic absorption resulting in nil systemic side effects.

  • 3

    Low risk of complications and adverse effects locally.

  • 4

    Avoidance of ‘first pass’ metabolism.

  • 5

    Reduced quantity of the drug required.