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. 2019 Jul 30;15(2):67–73. doi: 10.1016/j.joto.2019.07.001

Table 2.

Methods of intratympanic drug delivery.

  • 1

    Intratympanic (IT) injections (performed in anteroinferior/posteroinferior quadrant with or without a second paracentesis in anterosuperior/anteroinferior quadrant to act as a vent for the middle air escape during the injection of the solution).

  • 2

    Drug deposition onto absorbable material (absorbable gelatin sponge, Poly Lactic-co-Glycolic acid implantsa placed in round window niche.

  • 3

    Ventilation tube placement for drug instillation in the form of ear drops.

  • 4

    Placement of Silverstein MicroWick and Round Window Microcatheter for sustained drug delivery.b