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. 2020 Apr 15;8(4):574. doi: 10.3390/microorganisms8040574

Table 1.

Process parameters of the most promising organic acids produced by Y. lipolytica. SSF: solid state fermentation; RBC: repeated batch culture; isFBB: in situ fibrous bed bioreactor; FB: fed-batch.

Metabolite Substrate Y. lipolytica Strain Process Production Parameters Reference
Citric acid Pineapple waste NCIM3589 SSF 202 g/kg [30]
Inulin AWG7 INU8 RBC 203 g/L, 0.51 g/(L·h), 0.85 g/g [37]
Iso-citric acid Ethanol VKMY-2373 RBC 109 g/L, 1.35 g/(L·h), 0.8 g/g [54]
Succinic acid Raw glycerol PGC01003 isFBB 209 g/L, 0.65 g/(L·h), 0.42 g/g [81]
Okare NCYC2904 SSF 34 g/kg [80]
α-ketoglutarate Raw glycerol H355 Batch 186 g/L, 1.75 g/(L·h), 0.36 g/g [85]
Itaconic acid Glucose Po1f FB 22 g/L, 0.05 g/(L·h), 0.06 g/g [93]