Table 3.

Concentration of MC-LR and MC-LR-Cys in the liver of Lepr^db/J mice gavaged with 50 µg or 100 µg MC-LR per kg bodyweight.

Mouse	MC-LR Dosage	Time after Final Gavage	MC-LR Concentration (ng/g)			MC-LR-Cys Concentration (ng/g)
			Individual	Average	Standard Deviation	Individual	Average	Standard Deviation
1	50 µg/kg	2 h	14.21	12.64	5.37	1.17	2.77	1.38
2			8.37			4.38
3			8.41			2.21
4			19.57			3.31
5		4 h	11.45	12.17	5.01	2.16	2.90	1.00
6			15.55			3.16
7			14.51			4.15
8			3.63			1.65
9			7.18			3.41
10	100 µg/kg	2 h	12.95	16.38	3.96	5.10	7.23	2.03
11			14.78			7.44
12			22.05			*
13			15.72			9.14
14		4 h	18.54	13.50	4.42	13.83	11.24	2.37
15			10.29			9.16
16			11.66			10.75

*MC-LR-Cys concentration in the liver of mouse 12 was found to be an outlier using Grubbs’ test with 95% confidence.