Table 3.

Disease outcome in pigs inoculated following challenge with the highly virulent strain PRV-GX.

Group	Fever (≥40.5 °C)	Days to Fever Onset	Fever Frequency	Survival Rate	Viral Shedding
PBS	4/4	2	21/25 a	0/4	4/4
rGX-△gE/gI	0/4	-	0/64	4/4	0/4
rGX-△TK/gE/gI	0/4	-	0/64	4/4	0/4

Groups of pigs (n = 4) were inoculated with 10⁶ TCID50 of rGX-△TK/gE/gI or rGX-△gE/gI or PBS and then challenged with 1 mL 10⁷ TCID50/100 μL of the PRV-GX strain at 49 days post-inoculation (dpi). Following challenge, fever, days to fever onset, fever frequency, and survival were recorded. Fever is defined as rectal temperature ≥40.5 °C. ^a, Days with fever/total days observed.