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. 2020 Mar 27;8(4):479. doi: 10.3390/microorganisms8040479

Figure 9.

Figure 9

Effect of Lactobacillus fermentum UCO-979C or L. fermentum CRL973 EPS on cytokine and chemokine production of human macrophages (THP-1 cells) after Helicobacter pylori challenge. THP-1 cells were incubated with 100 μg/mL of L. fermentum UCO-979C or L. fermentum CRL973 EPS for 24 h. Then, cells were challenged with H. pylori 43504. The levels of TNF-α, IL-6, IFN-γ and IL-10 (pg/mL) in culture supernatants were determined 24 h after infection. The results represent data from three independent experiments. Results are expressed as mean ± standard deviation. Significant differences when compared to the control group: * (p < 0.05), ** (p < 0.01). Significant differences when compared to the indicated group: † (p < 0.05).