Figure 8.
Regulation of the eukaryotic initiation factor 4 (eIF4) and p70S6K signaling. Genes with overlapping actions observed in (A) Tat−/Meth vs. Tat−/Sal and in (B) Tat+/Meth vs. Tat−/Meth, and assigned to the regulation of eIF4 and p70S6K signaling were loaded into Cytoscape via Genemania; significant changes associated to assigned comparisons (p < 0.01) were visualized by loading the node attributes table. Tat−/Meth vs. Tat−/Sal p = 7.55 × 10−6 and Tat+/Meth vs. Tat−/Meth p = 7.53 × 10−6, with 51.8% and 48.9% overlap, respectively.