Table 2.
Forty most downregulated genes in Tat−/Meth animals as compared with Tat−/Sal.
| GeneSymbol | Gene Name | Tat−/Meth vs. Tat−/Sal Fold Change | FDR_BH p Value |
|---|---|---|---|
| Bard1 | BRCA1 associated RING domain 1 | −50.62054 | 1.49 × 10−12 |
| Sall4 | sal-like 4 (Drosophila) | −36.81502 | 1.31 × 10−11 |
| Krtap10-10 | keratin associated protein 10-10 | −28.0749 | 9.03 × 10−15 |
| Krtap8-2 | keratin associated protein 8-2 | −27.74784 | 5.26 × 10−11 |
| Olfr1350 | olfactory receptor 1350 | −26.34379 | 7.71 × 10−8 |
| Klk11 | kallikrein related-peptidase 11 | −25.88588 | 6.23 × 10−7 |
| Krtap5-5 | keratin associated protein 5-5 | −25.47586 | 3.83 × 10−12 |
| Sox13 | SRY-box containing gene 13 | −25.23627 | 6.90 × 10−13 |
| Elane | elastase, neutrophil expressed | −23.62923 | 1.70 × 10−13 |
| Baiap2l2 | BAI1-associated protein 2-like 2 | −22.7781 | 3.03 × 10−14 |
| Obp1a | odorant binding protein Ia | −22.46356 | 7.77 × 10−11 |
| C87414 | expressed sequence C87414 | −21.31501 | 4.89 × 10−2 |
| Chrna2 | cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) | −20.67663 | 7.91 × 10−12 |
| Vax2 | ventral anterior homeobox containing gene 2 | −20.52762 | 3.65 × 10−13 |
| Myod1 | myogenic differentiation 1 | −19.55757 | 3.01 × 10−6 |
| Lman1l | lectin, mannose-binding 1 like | −19.06574 | 8.39 × 10−8 |
| Tbx10 | T-box 10 | −19.04252 | 3.88 × 10−7 |
| Uimc1 | ubiquitin interaction motif containing 1 | −18.35725 | 1.63 × 10−9 |
| Adat1 | adenosine deaminase, tRNA-specific 1 | −17.68073 | 7.22 × 10−11 |
| Notum | notum pectinacetylesterase homolog (Drosophila) | −17.47123 | 8.13 × 10−14 |
| 4Sun5 | Sad1 and UNC84 domain containing 5 | −17.39883 | 5.34 × 10−8 |
| H2−Ob | histocompatibility 2, O region beta locus | −16.88096 | 5.41 × 10−14 |
| Msx2 | homeobox, msh-like 2 | −16.50882 | 7.78 × 10−7 |
| Pgc | progastricsin (pepsinogen C) | −15.78614 | 1.38 × 10−11 |
| Slc45a3 | solute carrier family 45, member 3 | −15.57587 | 3.57 × 10−13 |
| Aldh3a1 | aldehyde dehydrogenase family 3, subfamily A1 | −15.56452 | 1.23 × 10−13 |
| Apobec3 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3 | −15.04451 | 2.72 × 10−14 |
| Cd79a | CD79A antigen (immunoglobulin-associated alpha) | −14.53746 | 1.52 × 10−6 |
| Zglp1 | zinc finger, GATA-like protein 1 | −14.42331 | 1.60 × 10−13 |
| Tm4sf5 | transmembrane 4 superfamily member 5 | −14.26034 | 6.67 × 10−11 |
| Pom121l2 | POM121 membrane glycoprotein-like 2 (rat) | −14.03769 | 2.06 × 10−11 |
| Gng4 | guanine nucleotide binding protein (G protein), gamma 4 | −13.83425 | 6.72 × 10−7 |
| Cym | chymosin | −13.65853 | 9.79 × 10−14 |
| Tsga10ip | testis specific 10 interacting protein | −13.288 | 1.21 × 10−9 |
| Msi1 | Musashi homolog 1(Drosophila) | −13.23837 | 7.31 × 10−11 |
| Olfr1243 | olfactory receptor 1243 | −12.73216 | 1.03 × 10−8 |
| Atp6v1g3 | ATPase, H+ transporting, lysosomal V1 subunit G3 | −11.99044 | 4.40 × 10−10 |
| Casp14 | caspase 14 | −11.97585 | 2.44 × 10−12 |
| Tgif2lx1 | TGFB−induced factor homeobox 2-like, X-linked 1 | −11.71554 | 8.92 × 10−8 |
| Tmem146 | transmembrane protein 146 | −11.54644 | 1.41 × 10−10 |