Table 2.

The parameters Dm, m, and r are the antilog of x-intercept, the slope, and the linear correlation of the median-effect plot, which means the shape of the dose–effect curve, the potency (IC₅₀), and the conformity of the data to the mass action law, respectively [30,31]. Dm and m values are used for calculating the combination index (CI) value (CI < 1, =1, and >1 indicate synergism (Syn), additive (Add) effect, and antagonism (Ant), respectively. IC_50, IC₇₅, and IC₉₀ are the doses required to inhibit proliferation at 50%, 75%, and 90%, respectively. CalcuSyn software automatically provided theses values.

Mycotoxin	Time (h)	Dm (µM)	m	r	IC Values
					IC50		IC75		CI90
α-ZEL	24	66.10	1.36	0.9679
	48	31.59	1.82	0.9726
	72	15.24	2.02	0.9873
β-ZEL	24	171.33	1.28	0.9709
	48	12.46	1.26	0.9715
	72	11.65	2.28	0.9464
BEA	24	21.65	0.98	0.9763
	48	3.68	1.24	0.9945
	72	2.59	1.40	0.9805
α-ZEL+BEA	24	3.05	1.36	0.9736	0.37 ± 0.33	Syn	0.34 ± 0.35	Syn	0.31 ± 0.38	Syn
	48	1.16	1.56	0.9933	0.50 ± 0.24	Syn	0.47 ± 0.26	Syn	0.44 ± 0.29	Syn
	72	1.34	1.54	0.94708	0.96 ± 0.86	Add	1.00 ± 0.51	Add	1.20 ± 1.30	Ant
β-ZEL+BEA	24	3.78	1.20	0.9698	0.29 ± 0.19	Syn	0.26 ± 0.21	Syn	0.24 ± 0.24	Syn
	48	4.81	3.04	0.7744	3.24 ± 0.42	Ant	1.94 ± 0.32	Ant	1.00 ± 0.14	Add
	72	1.89	3.14	0.7585	1.35 ± 0.51	Ant	1.00 ± 0.12	Add	0.60 ± 0.52	Syn
α-ZEL+β-ZEL	24	133.46	1.73	0.7782	2.80 ± 1.01	Ant	2.32 ± 0.51	Ant	1.92 ± 0.62	Ant
	48	19.12	3.40	0.7782	2.14 ± 0.23	Ant	1.35 ± 0.18	Ant	0.30 ± 0.14	Syn
	72	7.89	5.01	0.9409	2.60 ± 0.90	Ant	1.42 ± 0.63	Ant	0.45 ± 0.42	Syn
α-ZEL+β-ZEL+BEA	24	3.74	3.14	0.9478	0.57 ± 0.30	Syn	0.32 ± 0.20	Syn	0.19 ± 0.14	Syn
	48	0.01	0.43	0.7465	0.23 ± 0.06	Syn	0.15 ± 0.07	Syn	0.18 ± 0.10	Syn
	72	7.47	2.30	0.8966	8.54 ± 0.77	Ant	7.60 ± 0.85	Ant	6.88 ± 0.95	Ant